Patented self-emulsifying vitamin delivery system with a complete spectrum of Tocotrienols and high bioavailability
DavosLife E3 Bio-Enhanced 20 is a patented self-emulsifying vitamin delivery system. This formulation contains the complete spectrum of Toco-trienols with α-Tocopherol and offers 46% higher bioavailability compared to a market sample. A higher bioavailability leads to a higher concentration of Vitamin E in the body, maximising the benefits of neutralising free radicals and reducing chronic inflammation. Tocotrienols are up to 60 times stronger in antioxidant activity compared to α-Tocopherol with unique anti-inflammatory properties.
Clinically proven enhanced absorption
Davos Life Science commissioned an opened-label, randomised, 4-way cross-over clinical study to compare the bioavailability of DavosLife E3 Bio-Enhanced 20 with a market sample. This study was conducted on 28 healthy volunteers with a dosage of 200 mg Tocotrienols. DavosLife E3 Bio-Enhanced 20 delivers a higher concentration of Tocotrienols (Cmax) to plasma compared to the market sample at the same time point (Figure 1).
![Plasma total tocotrienols graph](https://www.alsiano.com/wp-content/uploads/2019/06/davos-figur1-1024x587.jpg)
The Area Under the Curve (AUC) of Figure 1 represents the overall exposure of the body to Tocotrienols over time. DavosLife E3 Bio-Enhanced 20 has a greater AUC compared to the market sample and therefore the higher bioavailability between the two (Figure 2).
![Compartive graph of the bioavailability of Davoslife E3 Bio-enhanced 20](https://www.alsiano.com/wp-content/uploads/2019/06/davos-figur2-768x457.jpg)
More individual isomers delivered to plasma
Higher concentrations of each individual Tocotrienols isomer is delivered to plasma compared to the market sample (Figure 3).
![graph of individual Tocotrienol isomer delivered to plasma compared to market sample](https://www.alsiano.com/wp-content/uploads/2019/06/davos-figur3-1024x537.jpg)