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Biopharmaceutical manufacturing places demanding requirements on raw-material quality, consistency and documentation.
We help Nordic biopharma manufacturers identify raw materials suited to their process and quality requirements, from media preparation and cell culture to purification and final formulation.
Our portfolio includes pharmaceutical-grade amino acids, high-purity inorganic minerals, process surfactants and pharmaceutical-grade polysorbates for applications across biopharmaceutical and biologics production.
Amino acids and inorganic minerals for nutrient supply, ionic balance, osmolality adjustment and pH buffering.
Pharmaceutical-grade amino acids and high-purity minerals for nutrient and trace-element supply, with amino acids supporting cell growth and protein synthesis.
Amino acids and inorganic minerals for protein processing, process buffers and purification, as well as a non-ionic surfactant for viral inactivation.
Amino acids and inorganic minerals for ultrafiltration and buffer-exchange processes.
Amino acids and minerals for selected formulation and protein-stabilisation functions, together with pharmaceutical-grade surfactants for stabilisation, solubilisation and emulsification.
Amino acids play several roles in biopharmaceutical manufacturing. In cell culture and fermentation they provide nutrients that support cell growth and protein synthesis. Selected amino acids can also support buffering, protein stabilisation and other formulation functions in downstream processing and final formulation.
Our portfolio includes pharmaceutical-grade, multi-compendial amino acids for applications across upstream, downstream and formulation processes.
Available amino acids include glycine, L-arginine, L-aspartic acid, L-cysteine, L-glutamic acid, L-glutamine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-serine, L-threonine, L-tryptophan, L-tyrosine and L-valine. Selected amino acids are available in different forms, including HCl salts.
Cell culture media · Fermentation media · Protein processing · Biologics formulation
Pharmaceutical grade · Multi-compendial
Consistent mineral composition is important in cell culture, where variation in trace elements can affect cell growth, process performance and product quality.
We supply high-purity inorganic minerals for media preparation, cell culture, fermentation, process buffers, purification and formulation.
Depending on the application, inorganic minerals can provide nutrients and trace elements or support ionic balance, osmolality adjustment, conductivity control and pH buffering. Selected minerals can also be used in protein precipitation, fractionation and stabilisation.
Our range includes ammonium salts and salts of calcium, copper, iron, magnesium, manganese, phosphate, potassium, sodium and zinc.
For applications with stricter purity requirements, selected products are available as multi-compendial and low-endotoxin options.
Media preparation · Cell culture · Fermentation · Process buffers · Purification · Formulation
High purity · Multi-compendial · Selected low-endotoxin options
Ultra high purity inorganic salts with exceptionally low levels of impurities. We guarantee lot-to-lot consistency of trace elements which is critical to cell growth, since changes in levels of elemental impurities can cease growth. Furthermore, changes can also impact therapeutic attributes.
Heavy metal 1 ppm maximum
Arsenic (As) 0.1 ppm maximum
Lead (Pb) 0.1 ppm maximum
Mercury (Hg) 1 ppm maximum
Surfactants such as polysorbates can support the stability, solubilisation and formulation of sensitive biological active ingredients.
Our portfolio includes pharmaceutical-grade polysorbates for biologics and injectable formulations.
MONTANOX™ 20 HPB – Polysorbate 20
A non-ionic surfactant for stabilisation and solubilisation of biologics, including monoclonal antibodies, recombinant proteins and vaccines. Learn more >
MONTANOX™ 80 PPI – Polysorbate 80
A non-ionic surfactant for emulsification and solubilisation of poorly soluble and sensitive active ingredients in injectable formulations.
Surfactants can serve different functions across biopharmaceutical manufacturing, from viral inactivation in downstream processing to emulsification in final formulation.
Our portfolio includes surfactants for selected biomanufacturing and pharmaceutical applications.
SIMULSOL SL 11 W BM – Alkylpolyglucoside
SIMULSOL SL 11 W BM is a non-ionic surfactant for viral inactivation in the production of recombinant proteins, monoclonal antibodies and plasma-derived products.
MONTANE™ 20 PPI – Sorbitan laurate
MONTANE™ 20 PPI is a pharmaceutical-grade surfactant for emulsification in water-in-oil injectable formulations.
Lene Aarøe Nissen
Head of Nordic Sales
+45 22 70 10 02
lan@alsiano.com
