Powerful NatIng extracts for development of advanced metabolic formulations, aligned with new regulatory and market demands
In recent years, the debate on monacolins from fermented red rice resulted in a shift in the nutraceutical industry. The regulatory update that set a maximum limit of 2.9 mg of monacolin K has forced the sector to make a critical choice: continue using an ingredient now limited in efficacy, or innovate and propose alternatives that are truly safe, well-tolerated and backed by science.
NatIng has embraced the path of innovation. For years, the company has been dedicated to researching high-value natural ingredients designed to offer meaningful metabolic support. This commitment led to the development of AmaChol®, PataChol®, and BeramChol® – extracts derived from an innovative source: Amaranthus caudatus L. (amaranth), a naturally gluten-free plant rich in bioactive compounds.
AmaChol® - amaranth
AmaChol® is based on amaranth extracted with DEFS® technology that features in vitro studies conducted at the University of Genoa, which have demonstrated the extract’s ability to:
- reduce insulin secretion (-63.4% compared to the control)
- positively modulate the glycemic index (lower than maltodextrin)
- inhibit intestinal absorption of cholesterol by up to 69%
These preclinical data are also reflected at the clinical level: in an observational study on overweight subjects with glucose intolerance, AmaChol® led to a significant reduction in post-prandial glycemia, glycated hemoglobin, total cholesterol and LDL, with an improvement in BMI and body composition.
PataChol® - sweet potato and amaranth
Launched at Vitafoods Europe 2025 in Barcelona, PataChol® is a new sweet potato (Ipomoea batatas) extract supported with AmaChol® amaranth matrix. This combination is designed to effectively replace monacolins, maintaining high standards of safety, tolerability and naturalness. Clinical studies show that PataChol® supports the maintenance of metabolic homeostasis, supports glucose and lipid metabolism, and promotes intestinal balance.
BeramChol® - bergamot and amaranth
BeramChol® extract combines the lipid-lowering properties of bergamot (Citrus bergamia) with those of amaranth. Studies and international publications have confirmed the effectiveness of bergamot in reducing triglycerides, LDL cholesterol and improving HDL, making it an ideal choice for supporting the lipid profile in a natural, safe and sustainable way.
NatIng’s DEFS® extraction method
DEFS®(Dynamic Enhancer Flow System) is NatIng’s proprietary extraction process designed to activate the full phytocomplex of plant extracts, giving its products their distinctive properties. This advanced method treats the vegetative parts of plants under precisely controlled conditions, triggering the release of valuable phytonutrients. Inspired by ultrasonic technologies, the DEFS® process integrates these principles with NatIng’s own rigorous system of real-time monitoring—tracking key parameters such as frequency, pressure, temperature, and pH to ensure consistent and effective extraction. The result is a standardised, high-performance process that preserves the integrity and potency of natural ingredients.
