Cosmetic ingredients for soothing and repairing the skin

BISABOLIFE® is a natural soothing ingredient containing alpha-bisabolol also known as levomenol. It is recognised for its anti-inflammatory, antioxidant, mildly astringent and healing properties, and can calm irritation of sensitive and reactive skin and scalp. Besides that, it fortifies and soothes skin and restores its comfort. Historically, this ingredient was extracted from Wild chamomile (Matricaria recutita), however, this was a non-sustainable process, and has now been replaced by a novel highly efficient and sustainable biotechnology process generating high purity (>99%) (-)-α-bisabolol with the lowest farnesol content (<0.05 %) on the market. The ingredient obtained by this process is strictly identical to the natural plant active isomer of (-)-α-bisabolol.

Biological benefits of BISABOLIFE®:

• Soothing the skin by inhibiting 5-lipoxygenase, IL-1α, Il-6 and TNF-α
• Antioxidant by interfering with ROS (reactive oxygen species)
• Anti-infective properties
• Increasing bioavailability of molecules
• Skin brightening properties, inhibiting melanogenesis
• Exhibits immediate soothing effect even in rinse-off applications

BISABOLIFE® is a preservative-free, liposoluble, colorless to pale yellow viscous liquid. Dosage: 0.1-1%. Claims: Soothing, antioxidant, redness reduction, irritation reduction.

Sensityl™ is a patent-pending active cosmetic ingredient of natural origin. It is derived from the most active compounds of the microalgae Phaeodactylum tricornutum and developed using advanced marine biotechnology. Sensityl™ offers soothing and calming actions to the skin by rebalancing sensitive skin microbiota and taking control over the whole inflammation process. It reduces redness, soothes the skin and helps to enhance the mood.

Benefits of Sensityl™:

• Rebalancing and protecting skin microbiota
• Reducing the immune cell recruitment
• Reducing the pro-inflammatory mediators (IL-8)
• Decreasing the pain sensation
• Increasing the anti-microbial defenses of the skin
• Powerful soothing benefits in only one month
• Positively influences consumers mood

Sensityl™ is a clear yellow, water-soluble liquid.
Dosage: 1-3%.

Claims: Soothing, calming, neuro-soothing, indirect mood enhancer, skin reactivity inhibitor, sensitive skin pacifying, skin microflora rebalancing, protecting and enhancing skin microbiota composition.

The skin is particularly susceptible to the harmful effects of oxidation due to UV exposure. Thus, to protect the skin, the body normally produces a stream of antioxidants to neutralise the free radicals that are constantly being generated from metabolic activities. However, aging appears to weak this line of defense. Besides that, stress also seem to generate pro-oxidants which is adding on to cellular damage. Vitamin E tocoentriol is a well-known natural antioxidant, whose safety and efficacy are clinically tested and proven. Tocoentriols have excellent antioxidant potency and anti-inflammatory properties. The skincare benefits of tocoentriols are evidence-based.

Scientific tests of tocoentriols have shown:

• Increased collagen production.
• Significant reduction of oxidative stress markers.
• Reduction of melanin production in 9 days.
• Prevention of skin pigmentation following UV irradiation.
• Reduction of skin redness, skin itchiness, and reduction of skin blisters – after exposure to UV rays.
• Stimulation of skin repair two times faster than α-tocopherol.

DAVOSLIFE E3 DVL is a powerful natural active ingredient that contains the complete spectrum of tocotrienols and α-tocopherol. It is naturally derived from sustainable, non-GMO palm fruits and helps protecting the skin from oxidative stress and inflammation, this way help soothing and calming the skin. DAVOSLIFE E3 DVL is non-irritating to the skin and eyes and is safe to use in cosmetics.
DAVOSLIFE E3 DVL is available in different concentrations:

• DAVOSLIFE E3 DVL 50: Conc. 50%, yellow liquid
• DAVOSLIFE E3 DVP 84: Conc. 84%, yellow liquid
• DAVOSLIFE E3 DVL 95: Conc. 95%, yellow-orange liquid

The skin barrier, also known as the stratum corneum, is a thin layer of the outermost part of the skin that acts as a protective barrier against external aggressors such as pollutants, irritants, and microorganisms. This barrier is mainly composed of:

• Lipids, mostly ceramides, which require PUFA (PolyUnsaturated Fatty Acids) to be produced, and
• Corneocytes immersed in the lipidic matrix.

When the barrier is impaired, excessive water loss takes place and conditions like skin dryness, itching, eczema and dermatitis may occur, resulting in unhealthy skin. Blueberry (Vaccinium myrtillus L.) seeds are a natural source of the valuable PUFA and contain up to 20% of linoleic acid and α-linolenic acid in an optimal ration.

OMEGABLUE® is an upcycled active ingredient from bilberry seeds containing the essential fatty acids crucial for the formation of the skin barrier. When applied to the skin in cosmetic formulations, it improves the hydration and skin barrier function, and helps soothing the skin.

Biological benefits of OMEGABLUE®:

• Prevents dryness, irritation, and desquamation (the process of shedding off dead skin cells),
• Has anti-aging and restructuring properties,
• Protects and restores the skin barrier.

OMEGABLUE® is a preservative-free, oil-soluble and oily dark green substance.

Dosage: 2-10%. Claims: Skin barrier protection and recovery, damage skin repairing, post cleaning skin repairing, chronic inflammation damaged skin barrier.