17 November 2021
Vitamin E nutrients Tocotrienols have wide-reaching, clinically proven health benefits
Part of the vitamin E family, Tocotrienols are potent antioxidants and anti-inflammatory agents. Tocotrienols have clinically proven health benefits within the following areas:
- Tocotrienols have unique cholesterol lowering properties that are not shared by α-Tocopherol (1,4).
- Supplementation with Tocotrienols improved plasma total cholesterol, triglycerides and high-density lipoproteins (HDL) when compared to placebo (2,3).
- α-Tocotrienol is the most potent neuroprotective Vitamin E isomer (5).
- It is more effective than α-Tocopherol in preventing glutamate-induced brain injury and death (1).
- Tocotrienols are clinically proven to improve liver health biomarkers and liver pathophysiology in non-alcoholic fatty liver disease patients (6).
- Tocotrienols improve bone density by increasing osteoblast number, mineral deposition, bone formation activity, and decreasing osteoblast number, erosion on bone, and bone resorption activity (1).
- In contrast the bone protecting benefits of α-Tocopherol are inconsistent and contradictory (7).
- Tocotrienols have skin lightening properties8, which is no seen in α-Tocopherol.
- Clinical trials have confirmed Tocotrienols’ efficiency in reducing skin redness and pigmentation following UV irradiation (9).
- Tocotrienols stimulate collagen synthesis in the skin (10).
Naturally derived Tocotrienol
Davoslife E3 is a line of Tocotrienols products naturally derived from non-GMO palm fruits (Elaeis guineensis) sourced directly from RSPO-certified plantations. They contain a full spectrum of Tocotrienol isomers (α-, β-, γ-, δ-) and α-Tocopherol at a perfectly balanced ratio. Davoslife E3 complies with major international regulatory standards on Persistent Organic Pollutants (POPs) and other contaminants in food and health supplements.
Dosage recommendations: 50-100 mg Tocotrienols daily for overall wellness.
1. Peh et al. (2016). Pharmacology & Therapeutics, 162: 152 – 169.
2. Zaiden et al. (2010). Journal of Atherosclerosis and Thrombosis, 17(10): 1019 – 1032.
3. Daud et al. (2013). Vasc. Health Risk Manag., 9: 747 – 761.
4. Wade et al. (2013). Atherosclerosis, 226: 392 – 397.
5. Sen et al. (2010). J Am Coll Nutr., 29 (3): 314S – 323S.
6. Pervez et al. (2018). Turk J. Gastroenterol, 29: 170 – 6
7. Chin and Ima-Nirwana (2014). Nutrients, 6: 1424 – 1441.
8. Yap et al. (2010). Pigment Cell Melanoma Res., 23(5): 688-692. Yap, WN. (2017).
9. J. Cosmet. Dermatol. : 1-11.
10. Makpol et al. (2011). Arch Med. Sci., 889 - 895