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Get the most out of Tocotrienols with Davoslife E3 Bio-Enhanced 20

Get the most out of Tocotrienols with Davoslife E3 Bio-Enhanced 20

21 June 2019

Patented self-emulsifying vitamin delivery system with a complete spectrum of Tocotrienols and high bioavailability

DavosLife E3 Bio-Enhanced 20 is a patented self-emulsifying vitamin delivery system. This formulation contains the complete spectrum of Toco-trienols with α-Tocopherol and offers 46% higher bioavailability compared to a market sample. A higher bioavailability leads to a higher concentration of Vitamin E in the body, maximising the benefits of neutralising free radicals and reducing chronic inflammation. Tocotrienols are up to 60 times stronger in antioxidant activity compared to α-Tocopherol with unique anti-inflammatory properties. 


Clinically proven enhanced absorption 

Davos Life Science commissioned an opened-label, randomised, 4-way cross-over clinical study to compare the bioavailability of DavosLife E3 Bio-Enhanced 20 with a market sample. This study was conducted on 28 healthy volunteers with a dosage of 200 mg Tocotrienols. DavosLife E3 Bio-Enhanced 20 delivers a higher concentration of Tocotrienols (Cmax) to plasma compared to the market sample at the same time point (Figure 1). 

 

Figure 1: Plasma Total Tocotrienols

Figur 1: Total Plasma Tocotrienols

 


The Area Under the Curve (AUC) of Figure 1 represents the overall exposure of the body to Tocotrienols over time. DavosLife E3 Bio-Enhanced 20 has a greater AUC compared to the market sample and therefore the higher bioavailability between the two (Figure 2). 

 

 

Davoslife E3 Bio-Enhanced 20


More individual isomers delivered to plasma 

Higher concentrations of each individual Tocotrienols isomer is delivered to plasma compared to the market sample (Figure 3).  

 

More individual isomers delivered to plasma

Figure 3